产品描述 概述Recombinant Human S100 Calcium Binding Protein A8 is produced by our E.coli expression system and the target gene encoding Met1-Glu93 is expressed with a 6His tag at the C-terminus. 使用说明This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. 技术规格Tag | C-6His | 种属 | Human | 表达系统 | E.coli | Accession# | P05109 | Source | E.coli | Formulation_Description | Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 2.5mM EDTA, 10% Glycerol, pH 7.0. | Storage | Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. | Purity | Greater than 95% as determined by reducing SDS-PAGE. | Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. | Background | Protein S100-A8 (also MRP8 and calgranulin A) is a calcium- and zinc-binding protein.It plays a prominent role in the regulation of inflammatory processes and immune response. S100A8 can induce neutrophil chemotaxis and adhesion. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. It can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread. |
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