产品描述 概述Recombinant Human Probable Xaa-Pro Aminopeptidase 3 is produced by our E.coli expression system and the target gene encoding Met1-Ser507 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus. 使用说明This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. 技术规格| Tag | N, C-6His | | 种属 | Human | | 表达系统 | E.coli | | Accession# | Q9NQH7 | | Source | E.coli | | Formulation_Description | Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3. | | Storage | Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. | | Purity | Greater than 95% as determined by reducing SDS-PAGE. | | Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. | | Background | Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure. |
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